Pelican Cases http://pelican.com/home.php
Not warranted for shark bite bear attacks or kids under 5 so pretty much indestructable and if they do break they always back you up. Had a mate break a handle on one that was 10 years old and they replaced it without question.
The other alternate if your carrying your cameras is just a nondescript backpack with a bit of foam padding. They work well and dont have expensive cameras inside labelled all over them. Some crooks do their research to and know what they are looking for. If they just see some ratty old backpack they might pass you over for the next person.
I used to use a pelican 1510, but it got a tad small. I now use a Seahorse case that is very similar to the Pelican, but larger and somewhat lighter. It is legal carry-on and I have had no trouble getting it on a plane. It is a rolling case, which is essential. Since it is a hard case, I can use it as a seat whenever you are standing around too long.
On a few occasions, I almost got a hernia getting it into the overhead trying to make it look like the 15 pound limit most carriers require. It comes nowhere close to that, I can assure you!
The few times I had to gate check it, I was never worried about heavy stuff landing on top of it. I can't say I would be that happy with a soft case under those circumstances.
I use the padded dividers that came with my 1510. They are smaller, but I pack my tray and arms along the edges.
I love it!!